How does Thymalin differ from Thymosin Alpha-1?

Thymosin Alpha-1 (Ta1) is a specific, well-characterised 28-amino acid peptide with known receptor targets (TLR2/9) and extensive clinical trial data. Thymalin is a mixture of shorter thymic peptides (primarily dipeptides and tripeptides) developed under the Khavinson peptide bioregulator framework. Thymalin's mechanism is proposed to be epigenetic regulation through gene activation rather than specific receptor binding. They target overlapping but not identical immune pathways.

What is the 15-year follow-up study showing?

The Anisimov/Khavinson 2009 study followed elderly patients treated with Thymalin and/or Epithalon vs controls over 15 years. The treated group showed approximately 2x lower all-cause mortality at the 15-year mark. While this is observational rather than a blinded RCT, it is one of the longest-term human longevity studies ever conducted with peptide bioregulators and generated significant interest in the field.

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Thymalin

Name: Thymalin
Price: 129 USD
Availability: InStock

Short thymus-derived peptide bioregulator that restores T-cell function and immune competence in aging models. Used in Russian longevity research alongside

ImmuneAnti-Aging

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1+ vials

−5%

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−10%

5+ vials

−20%

10+ vials

Total Price

$130

For research & laboratory use only. Not for human consumption.

Half-Life

~1-3 hours

Administration Route

Subcutaneous injection

Thymus Gland Peptide

Khavinson peptide restoring age-related thymic involution

Immune Ageing

Reduces immunosenescence; restores T-cell output with age

Longevity Data

Combined epithalon + thymalin studies show 40% mortality reduction

Effect Profile

Based on primary research mechanisms

Immune Activation

Anti-Viral Defence

Inflammation Control

Immune Ageing

Mechanism of Action

Thymalin is a mixture of short thymic peptides (primarily di- and tripeptides: Lys-Glu, Ala-Glu-Asp-Gly) developed from thymus gland extract by the Khavinson group. Like other peptide bioregulators, these short sequences penetrate cell nuclei and activate organ-specific gene expression. In thymus and T-lymphocytes, they promote IL-2 production, restore T-helper/T-suppressor ratios, and increase NK cell activity. Long-term studies showed reduced all-cause mortality in elderly cohorts.