How does GHRP-2 compare to ipamorelin for GH release?

GHRP-2 typically produces a stronger GH pulse than ipamorelin at equivalent molar doses. However, it also stimulates cortisol and prolactin to a greater degree, which makes ipamorelin the preferred compound in protocols where those side effects are undesirable.

Does GHRP-2 increase appetite?

Yes, to a moderate degree. GHRP-2 is a ghrelin receptor agonist, and ghrelin is known as the 'hunger hormone.' GHRP-2 stimulates appetite less than GHRP-6 (which produces strong hunger effects) but more than ipamorelin.

Can GHRP-2 be combined with GHRH peptides?

Yes - GHRP-2 combined with CJC-1295 or sermorelin produces synergistic GH release. GHRP-2 (GHS-R1a) and GHRH analogues act through different receptors that converge on GH secretion, with the combination often producing 3-5x greater GH release than either alone.

GHRP-2

Name: GHRP-2
Price: 40 USD
Availability: InStock

Second-generation GHRP with potent GH-releasing activity and mild ghrelin-like effects on appetite, studied for GH deficiency, muscle preservation, and

GH BoostMuscleHormonal

● In Stock

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Quantity (vials)

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1+ vials

−5%

3+ vials

−10%

5+ vials

−20%

10+ vials

Total Price

$40

For research & laboratory use only. Not for human consumption.

Half-Life

~1-2 hours

Administration Route

Subcutaneous injection

Strong GH Pulse

Second only to GHRP-6 in peak GH stimulation potency

Lean Mass Preservation

Anti-catabolic during caloric restriction protocols

Fat Mobilisation

GH-driven lipolysis increases free fatty acid oxidation

Effect Profile

Based on primary research mechanisms

Muscle Growth

Fat Oxidation

Recovery Speed

Strength

Mechanism of Action

GHRP-2 (Pralmorelin) is a hexapeptide agonist of the ghrelin receptor (GHS-R1a) that stimulates pulsatile GH release from the anterior pituitary. It also weakly activates CD36 receptors involved in lipid uptake. Unlike ipamorelin, GHRP-2 stimulates moderate cortisol and prolactin elevation at higher doses, limiting its use in protocols where adrenal activity must remain unperturbed.